The goal is for everyone, including people experiencing homelessness, to be able to easily get a COVID-19 vaccine as soon as possible. However, because it is anticipated there will be a limited supply of vaccine at first, in December 2020, CDC adopted the Advisory Committee on Immunization Practices (ACIP) recommendation that healthcare personnel and residents of long-term care facilities receive COVID-19 vaccine first. These groups were chosen because health care settings in general, and long-term care settings in particular, can be high-risk locations for getting the virus that causes COVID-19. Healthcare personnel and residents of long-term care facilities will likely receive vaccine at the end of 2020 and in early 2021. Public health professionals at state and local health departments are now working on how to further distribute COVID-19 vaccines in a fair, ethical, and transparent way for additional groups, including considerations for people experiencing homelessness. People experiencing homelessness have many additional characteristics, such as age and employment in certain jobs, that will also influence when the vaccine will be available to them.